姓名：丛明

博士/教授/硕士生导师/博士生导师

个人履历

学习经历：

1996-2000烟台师范学院生物系 学士

2003-2005华南热带农业大学 硕士

2005-2008中国科学院海洋研究所 博士

工作经历：

2000-2003山东省蚕业研究所 研究实习员

2009-2020 中国科学院烟台海岸带研究所 助理研究员、副研究员

2020-2023 烟台大学海洋学院 副教授

2024-至今 烟台大学海洋学院 教授

主要科研领域与方向

着眼于我国近海频发的海洋污染事件，利用现代海洋分子生物学、组学(蛋 白质组学、转录组学、代谢组学、miRNA组学等)、细胞生物学和传统毒理学等 相结合的手段，重点关注海洋贝类的天然免疫、海洋污染物毒性效应及其致毒机 制，从中筛选海洋环境污染的生物标志物和毒性关键基因，以期用于海洋污染的 生物指示工作，并为海洋贝类养殖业的抗逆育种提供可靠的分子靶标；同时，利 用海洋生物对某些污染物的生物可利用性，对受损海洋环境进行生物治理与修复。

代表性论文

1. Cong M, Yu Y, Li Z, Li Y, Che Y, Lv J (2025). Transcriptomic and enzymatic analyses revealed synergistic toxicity of ammonia and nitrite on Ruditapes philipparum. Ecotoxicology and Environmental Safety, 301, 118521. (SCI 二区)

2. Cong M, Li Z, Tian W, Yu Y, Che Y, Lv J (2025). Increased miRNA-375 causes oxidative damage but promotes apoptosis resistance and cell migration in the clam Ruditapes philippinarum. Frontiers in Marine Science, 1528020. (SCI 二区)

3. Cong M, Li Z, Tian W, Li Y, Lv J (2024). Environmental concentration of ammonia nitrogen induced marked changes in proteome of clam Ruditapes philippinarum in dose- and time-dependent manner. Journal of Oceanology and Limnology, 42(5): 1634-1650. (SCI 二区)

4. Cong M, Li Z, Che Y, Li Y, Tian W, Lv J, Sun X (2024). Metabolomics revealed more deleterious toxicity induced by the combined exposure of ammonia and nitrite on Ruditapes philippinarum compared to single exposure. Marine Environmental Research, 196:106398 (SCI 二区)

5. Tian W, Li Y, Li Z, Lv Jn, Cong M(通讯作者)*. (2023) Comparative analysis of microRNA expression profiles in clam Ruditapes philippinarum after ammonia nitrogen exposure. Aquatic Toxicology, 261: 106624 (SCI一区)

6. Cong M, Xu H, Li Y, Tian W, Lv J (2022) Modifications of calcium metabolism and apoptosis after ammonia nitrogen exposure imply a tumorous fate in clam Ruditapes philippinarum?. Aquatic Toxicology, 245: 106110 (SCI一区)

7. Cong M, Li Y, Xu H, Lv J, Wu H, Zhao Y. (2021) Ammonia nitrogen exposure caused structural damages to gill mitochondria of clam Ruditapes philippinarum. Ecotoxicology and Environmental Safety, 222:112528 (SCI一区)

8. Cong M, Wu H, Cao T, Ji C, Lv J. (2019) Effects of ammonia nitrogen on gill mitochondria in clam Ruditapes philippinarum. Environmental Toxicology and Pharmacology 65:46-52. (SCI一区)

9. Lv J, Cao T, Ji C, Cong M(通讯作者)*, Zhao J, Wu H. (2019) Digital gene expression analysis in the gills of Ruditapes philippinarum after nitrite exposure. Ecotoxicology and Environmental Safety 184:109661. (SCI一区)

10. Lv J, Zhao J, Yang D, Wu H, Cong M(通讯作者)*. (2019) Tissue distribution and functional characterization of mytimacin-4 in Mytilus galloprovincialis. Journal of Invertebrate Pathology 166,107215. (SCI二区)

11. Cong M, Wu H, Cao T, Lv J, Wang Q, Ji C, Li C, Zhao J. (2018) Digital gene expression analysis in the gills of Ruditapes philippinarum exposed to short- and long-term exposures of ammonia nitrogen. Aquatic Toxicology 194:121-131. (SCI 一区)

12. Yang D, Zhang Q, Wang Q, Chen L, Liu Y, Cong M(通讯作者)*, Wu H, Li F, Ji C, Zhao J. (2018) A defensin-like antimicrobial peptide from the manila clam Ruditapes philippinarum: Investigation of the antibacterial activities and mode of action. Fish & Shellfish Immunology 80: 274-280. (SCI一区)

13. Wu H, Zhong M, Lu Z, Shan X, Li F, Ji C, Cong M(通讯作者)*. (2018) Biological effects of tris (1-chloro-2-propyl) phosphate (TCPP) on immunity in mussel Mytilus galloprovincialis, Environmental Toxicology and Pharmacology, 61:102-106. (SCI 一区)

14. Cong M, Wu H, Yan H., Zhao J, Lv J. (2017) Gill damage and neurotoxicity of ammonia nitrogen on the clam Ruditapes philippinarum. Ecotoxicology 26, 459 469. (SCI三区)

15. Cong M, Zhao J, Lv J, Ren Z, Wu H. (2016) Homologous cloning, characterization and expression of a halophyte phytochelatin synthase gene in Suaeda salsa. Chinese Journal of Oceanology and Limnology 34:1034-1043. (SCI二区)

16. 曹滕飞,丛明(通讯作者)*,李兆艳,赵建民,吕家森,李成华. (2017)氨态氮对菲律 宾蛤仔毒理机制研究的内参基因筛选.生态毒理学报12(2):182-190.34(4): 453 459. (中文核心)

17. 著作. 黄河三角洲生态农牧场构建原理与实践，2022.09. 骨干参编

近五年主持教学、科研项目

1. 2024/01-2026/12，环境相关浓度氨氮和亚硝氮复合暴露对菲律宾蛤仔的毒性效应研究，山东省自然科学基金面上项目，主持。

2. 2019/01 -2022/12，氨氮污染对菲律宾蛤仔鳃组织线粒体的损伤机制研究，国家自然基金面上项目, 主持。

3. 2019/01-2020/07，陆基水产养殖增效减排技术集成与试验示范，中国科学院战略性先导科技专项子课题，主持。

4. 2015/01-2017/12， 氨氮污染对菲律宾蛤仔鳃组织的靶向毒性效应研究,国家自然基金青年项目，主持。

5. 2015/01月-2018/12，新型褐藻资源养护技术研究，国家海洋局公益项目子课题3，骨干参与。

6. 2013/01-2015/12，氨态氮对菲律宾蛤仔的毒性研究，江苏省面上基金项目，主持。

联系方式

邮箱：mcong@ytu.edu.cn