
姓名:李学鹏
博士/副教授
个人履历:
2020.06-至今 烟台大学海洋学院 副教授
2017.09-2020.05 中国科学院海洋研究所 博士后
2014.09-2017.07 中国科学院海洋研究所 博士
2011.09-2014.07 中国海洋大学 硕士
2007.09-2011.07 曲阜师范大学 学士
主要科研领域与方向:
主要从事水产动物疾病与免疫防控研究。重点关注鱼类先天免疫抗菌机制, 海水病原微生物侵染宿主的机制,鱼类绿色抗菌肽和疫苗的研发。
代表性论文:
[1] Yue Fang, Xiao-Dong Xu, Sheng-Han Gao, Jian Zhang, Xuepeng Li*. From recognition to defense: the multifaceted functions of PoPGRP-2 and PoPGRP-5 in Paralichthys olivaceus immunity. Aquaculture (2025): 743252. (唯一通讯作者, 中科院二区Top/IF=3.9)
[2] Xiao-dong Xu, Ya-lin Wang, Kun-yu Zhao, Guan-yu Chen, Jian Zhang, Xuepeng Li* Unveiling PoPFP: A short-chain pentraxin involving antibacterial immunity in marine teleost. Int J Biol Macromol. 328 (2025) 147703. (唯一通讯作者,中科 院二区Top/IF=8.5)
[3] Sheng-han Gao, Jia-qi Sun, Kun-yu Zhao, Gang Li, Jian Zhang, Xuepeng Li*. Harnessing PoSAP, a serum amyloid P component in Japanese flounder (Paralichthys olivaceus) for superior antibacterial immunity in teleost fish. Aquaculture 609 (2025): 742859. (唯一通讯作者,中科院二区Top/IF=3.9)
[4] Ji-xing Feng, Sheng-jia Wang, Hong-ye Wang, Xuepeng Li*. Characterization and functional analysis of CsTLR13M/13S, two novel teleost toll-like receptor 13 in antimicrobial immunity. Aquaculture. 605 (2025): 742523. (唯一通讯作者,中科院二区Top/IF=3.9)
[5] Feng JiXing, Liu Ling, Wang HongYe, Zhang Jian*, Li Xuepeng*. A soluble TLR5 is involved in PBLs activation and antibacterial immunity via TLR5M MyD88-signaling pathway in tongue sole Cynoglossus semilaevis. Int J Biol Macromol. 230 (2023):123208. (共同通讯作者,中科院一区/IF=8.2)
[6] Chen GuanYu, Feng JiXing, Shi WenKai, Wang HongYe, Zhang Jian, Li Xuepeng*, PoClu, a teleost Clusterin, acts as a negative regulator in complement activation and antibacterial immunity. Aquaculture. 575 (2023): 739791. (通讯作者,中科院一区/IF=4.5)
[7] Li Xuepeng*,Chen Guanyu, Jin Qi, Lou Bangui, Liu Bingjian, Zhang Jian,Feng Ji-xing , Chen Tian-tian*. CsIL-11, a teleost interleukin-11, is involved in promoting phagocytosis and antibacterial immune defense. Int J Biol Macromol. 192 (2021):1021-1028. (首作+共同通讯作者,中科院一区/IF=6.953)
[8] Chen Guan-yu, Xu Xiao-dong, Feng Ji-xing, Zhang Jian, Li Xue-peng *. A single C1q A chain promotes leukocytes phagocytosis/chemotaxis and mediates bacterial clearance in Japanese flounder Paralichthys olivaceus. Aquaculture. (2024): 740840. (通讯作者,中科院一区/IF=3.9)
[9] Li Xuepeng*, Chen Guanyu, Zhang Jian, Li DengLai, Feng Jixing*. A teleost interleukin-16 is implicated in peripheral blood leukocytes recruitment and anti bacterial immunity. Int J Biol Macromol. 187 (2021):821-829. (首作+共同通讯 作者,中科院一区/IF=6.953)
[10] Chen Guan-yu, Zhao Kun-yu, Jin Qiu, Zhang Jian, Li Xue-peng*. A novel teleost C1q C chain (PoC1qC) participates in complement and leukocytes antibacterial immunity. Aquaculture. (2024): 740831. (通讯作者,中科院一区/IF=3.9)
[11] Li Xuepeng*, Sun Jiaqi, Sui Zhihai, Zhang Jian, Feng Jixing. Membrane orthologs of TLR5 of tongue sole Cynoglossus semilaevis: Expression patterns, signaling pathway and antibacterial property. Fish Shellfish Immunol. 126 (2022):131-140. (首作+通讯作者,中科院二区/IF=4.622)
[12] Zhao Kun-yu, Huang Hui, Jin Qiu, Wang Lei, Jiao Xu-dong*, Li Xue-peng*, CsIL-20, a tongue sole interleukin-20, negatively mediates leucocyte activity and antibacterial defense. Fish Shellfish Immunol. 145 (2024): 109325. (共同通讯, 中科院二区/IF=4.1)
[13] Sun JiaQi, Zhao KunYu, Zhang ZiXiang, Li Xuepeng*. Two novel teleost calreticulins PoCrt-1/2, with bacterial binding and agglutination activity, are involved in antibacterial immunity. Fish Shellfish Immunol. 143 (2023): 10920 (通讯作者,中科院二区/IF=4.7)
[14] Zhao KunYu, Fang Yue, Xu RongJing, Zhang Jian, Sun Bin*, Li Xuepeng*. PoIL8-L, a teleost interleukin-8 like, enhances leukocyte cellular vitality and host defense against bacterial infections in Japanese flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 153 (2024): 109876. (共同通讯作者,中科院二区/IF=4.1)
[15] Zhao KunYu, Chen Guan-yu, Huang Hui, Jiao XuDong, Li Xuepeng*, Zhang Jian*. PoCXCL8, a teleost chemokine, exerts direct bactericidal, chemotactic/phagocytic, and NETs releasing properties, promoting host anti bacterial immunity. Fish Shellfish Immunol. 154 (2024): 109874. (共同通讯作者, 中科院二区/IF=4.1)
近五年承担科研项目
1. 山东省教育厅,山东省高等学校青年创新团队发展计划(2022KJ269),牙鲆正五聚蛋白 PTX3 抗迟缓爱德华氏菌侵染的机制及应用研究,2023.01-2025.12。
2. 国家自然科学基金委员会,青年项目,半滑舌鳎白细胞介素-10抗细菌免疫机制研究(31802329), 2019-01至2021-12。
3. 中国博士后科学基金会,面上项目,半滑舌鳎TLR5信号途径及抗细菌免疫机制研究(2018M632733), 2018-05至2020-05。
4. 烟台大学,学科带头人项目启动基金(HX20B36),鱼类白介素抗菌机制研究,2020.06-2025.05。
5. 青岛市人力资源和社会保障局,迟缓爱德华氏菌侵染诱导的牙鲆microRNA功能研究,2018.05-2020.05。
6. 国家自然科学基金委员会,联合基金重点支持项目,山东省深远海养殖鱼类 病原菌哈维氏弧菌和美人鱼发光杆菌的致病机制(U24A201412),2025-01至 2028-01。
指导研究生情况: 已毕业研究生4人,在读5人,已考取博士2人,获取国家奖学金1人,山东省优秀硕士毕业论文1人,山东省优秀毕业生1人,山东省研究生创新成果奖2人。
联系方式:
邮箱:Lixuepeng20@ytu.edu.cn
办公室:海洋学院221
实验室风采
