姓名:李学鹏
博士/副教授
个人履历:
2020.06-至今 烟台大学海洋学院 副教授
2017.09-2020.05 中国科学院海洋研究所 博士后
2014.09-2017.07 中国科学院海洋研究所 博士
2011.09-2014.07 中国海洋大学 硕士
2007.09-2011.07 曲阜师范大学 学士
主要科研领域与方向:
主要从事水产动物疾病与免疫防控研究。重点关注鱼类先天免疫抗菌机制,海水病原微生物侵染宿主的机制,鱼类绿色疫苗、佐剂的研发及应用。
代表性论文:
1. Feng JX, Liu L, Wang HY, Zhang J, Li XP*. A soluble TLR5 is involved in PBLs activation and antibacterial immunity via TLR5M-MyD88-signaling pathway in tongue sole Cynoglossus semilaevis. Int J Biol Macromol. 2023 Mar 1;230:123208.(中科院1区,IF=8.025)
2. Li XP, Sun JQ, Sui ZH, Zhang J, Feng JX. Membrane orthologs of TLR5 of tongue sole Cynoglossus semilaevis: Expression patterns, signaling pathway and antibacterial property. Fish Shellfish Immunol. 2022 Jul;126:131-140 (Q2, 4.622)
3. Li XP*, Chen GY, Zhang J, Li DL, Feng JX*. A teleost interleukin-16 is implicated in peripheral blood leukocytes recruitment and anti-bacterial immunity. Int J Biol Macromol. 2021 Sep 30;187:821-829. (Q1, 8.025)
4. Li XP*, Chen GY, Jin Q, Lou FR, Liu BJ, Zhang J, Feng JX, Chen TT*. CsIL-11, a teleost interleukin-11, is involved in promoting phagocytosis and antibacterial immune defense. Int J Biol Macromol. 2021 Dec 1;192:1021-1028. (Q1, 8.025)
5. Li Xue-peng, and Zhang Jian*. Tongue sole (Cynoglossus semilaevis) interleukin 10 receptors are involved in the immune response against bacterial infection. Developmental & Comparative Immunology 115 (2020): 103885. (Q3, 3.605)
6. Li Xue-peng*, Jiang Shuai, Sun Bin, Zhang Jian*. Tongue sole (Cynoglossus semilaevis) interleukin 10 plays a negative role in the immune response against bacterial infection. Fish Shellfish Immunol. 95 (2019): 93-104. (Q2, 4.622)
7. Li Xue-peng, and Zhang Jian*. A live attenuated Edwardsiella tarda vaccine induces immunological expression pattern in Japanese flounder (Paralichthys olivaceus) in the early phase of immunization. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 239 (2020): 108872. (Q3, 4.520)
8. Li Xue-peng, and Sun Li*. Toll-like receptor 2 of tongue sole Cynoglossus semilaevis: Signaling pathway and involvement in bacterial infection. Fish Shellfish Immunol. 51 (2016): 321-328. (Q2, 4.622)
9. Li Xue-peng, and Sun Li*. A teleost complement factor Ba possesses antimicrobial activity and inhibits bacterial infection in fish, Developmental & Comparative Immunology 71 (2017): 49-58. (Q2, 4.622)
10. Li Xue-peng, and Hu Yong-hua*. CD94 of tongue sole Cynoglossus semilaevis binds a wide arrange of bacteria and possesses antibacterial activity. Fish Shellfish Immunol. 58 (2016): 641-649. (Q2, 4.622)
11. Li Xue-peng, Chi Heng, and Zhang Jian*. Beclin-1 is involved in tongue sole Cynoglossus semilaevis immune defense against bacterial infection. Fish Shellfish Immunol.77 (2018): 8-12. (Q2, 4.622)
12. Li Xue-peng, and Sun Li*. TLR7 is required for optimal immune defense against bacterial infection in tongue sole (Cynoglossus semilaevis). Fish Shellfish Immunol. 47.1 (2015): 93-99. (Q2, 4.622)
近五年主持教学、科研项目:
1. 山东省教育厅,山东省高等学校青年创新团队发展计划(2022KJ269),牙鲆正五聚蛋白PTX3抗迟缓爱德华氏菌侵染的机制及应用研究,2023.01-2025.12,40万元,在研,主持。
2. 烟台大学,学科带头人项目启动基金(HX20B36),鱼类白介素抗菌机制研究,60万,2020.06-2025.05,在研,主持。
3. 国家自然科学基金委员会,青年项目,半滑舌鳎白细胞介素-10抗细菌免疫机制研究(31802329),26万元,2019-01至2021-12,已结题,主持。
4. 中国博士后科学基金会,面上项目,半滑舌鳎TLR5信号途径及抗细菌免疫机制研究(2018M632733),5万元,2018-05至2020-05,已结题,主持。
5. 青岛市人力资源和社会保障局,迟缓爱德华氏菌侵染诱导的牙鲆microRNA功能研究,2018.05-2020.05,5万,已结题,主持。
6. 国家自然科学基金委员会,青年项目,315022197,肿大细胞病毒诱导的半滑舌鳎蛋白谱:重要免疫蛋白的功能解析及其在病毒疫病防控中的应用潜能,2016-01至2018-12,20万元,已结题,参加。
7. 山东省自然科学基金委员会,面上项目,ZR2020MC198,肿大细胞病毒泛素连接酶ORF64L在病毒感染中的作用机制,2021-01至2023-12,10万元,在研,参加。
联系方式:
邮箱:Lixuepeng20@ytu.edu.cn
QQ:709662179
办公室:海洋学院336
实验室风采