姓名：卢霞

博士/副教授/硕士生导师

个人履历

2003-2007 西北农林科技大学 学士

2007-2012 中国科学院海洋研究所 (保送) 博士 (硕博连读)

工作经历：

2012-2017 中国水产科学研究院黄海水产研究所 助理研究员

2018-2020 中国水产科学研究院黄海水产研究所 副研究员

2020-2023 中国科学院烟台海岸带研究所 副研究员

2024-至今 烟台大学海洋学院 副教授

主要科研领域与方向

主要从事贝类等水产动物重要性状遗传机制解析、分子育种、渔业资源评价与保护等方面的研究，利用群体遗传学、数量遗传学、分子生物学、生物信息学、分子遗传学及组学等方法和技术开展相关研究，助力“蓝色粮仓”健康

代表性论文

1. Yang Zhao, Junhao Ning, Quanchao Wang, Guilong Liu, Xin Xu, Rongjian Chen,  Chunde Wang*, Xia Lu (通讯作者)*. Potential roles of LMNA in promoting  longevity for larger Argopecten scallops. Aquaculture, 2025, 600:742254 (SCI, 中科院一区Top)

2. Yang Zhao, Junhao Ning, Yuan Wang, Guilong Liu, Xin Xu, Chunde Wang *, Xia  Lu (通讯作者)*. Potential roles of the sirtuins in promoting longevity for larger  Argopectenscallops.Marine Life Science & Technology, 2025,  DOI:10.1007/s42995-024-00269-3 (SCI, 一区 Top)

3. Tieying Yu, Chunde Wang, Jiawei Fan, Rongjie Chen, Guilong Liu, Xin Xu,m  Junhao Ning*, Xia Lu (通讯作者)*. Single-cell RNA sequencing revealed the  roles of macromolecule epidermal growth factor receptor (EGFR) in the hybrid  sterility of hermaphroditic Argopecten scallops. International Journal of Biological  Macromolecules, 2024, 280:136062 (SCI, 中科院一区Top)

4. Yang Zhao, Ke Yuan, Junhao Ning, Guilong Liu, Xin Xu, Chunde Wang*, Xia Lu(通讯作者)*. Potential roles of lipases and antioxidases on longevity under nutrientrestriction in two Argopecten scallops with distinct lifespans. International Journal  of Biological Macromolecules, 2024, 280, 136045 (SCI, 中科院一区Top)

5. Xinyu Song, Junhao Ning, Quanchao Wang, Guilong Liu, Xin Xu, Chunde Wang*,Xia Lu (通讯作者)*. Genome-wide analysis with additive and epistasis effects  reveals growth-related loci and candidate genes in hybrid Argopecten scallops.  Aquaculture, 2024, 589: 741018 (SCI, 中科院一区Top)

6. Tieying Yu, Fukai Wang, Junhao Ning, Guilong Liu, Xin Xu, Chunde Wang*, Xia  Lu (通讯作者)*. Effects of temperature on fertility in hybrid hermaphroditic  Argopecten scallops. Aquaculture, 2024, 581: 740468. (SCI, 中科院一区Top)

7. Tieying Yu, Junhao Ning, Min Chen, Yuan Wang, Guilong Liu, Quanchao Wang,  Xin Xu, Chunde Wang, Xia Lu (通讯作者)*. Hybrid sterility in hermaphroditic  Argopecten scallops: Mutated mitochondrial genes and abnormal expression of  nuclear genes. Aquaculture Reports, 2023, 31: 101652. (SCI, 中科院二区Top)

8. Tieying Yu, Junhao Ning, Min Chen, Fukai Wang, Guilong Liu, Quanchao Wang,  Xin Xu, Chunde Wang, Xia Lu (通讯作者)*. Potential involvement of DNA  methylation in hybrid sterility in hermaphroditic Argopecten scallops. Marine  Biotechnology, 2023, 25(5): 701-717. (SCI, Q1)

9. Yuan Wang, Chunde Wang, Junhao Ning, Tieying Yu, Ke Yuan, Guilong Liu,  Quanchao Wang, Xin Xu, Bo Liu, Xia Lu (通讯作者)*. Molecular characteristics  of IGF and IGF1R genes and their potential roles on longevity in two scallops with distinct lifespans. Aquaculture Reports, 2023, 33:101812. (SCI, 中科院二区Top)

10. Tieying Yu, Junhao Ning, Fukai Wang, Guilong Liu, Quanchao Wang, Xin Xu,  Chunde Wang, Xia Lu ( 通 讯 作 者 )*. Whole-genome re-sequencing and  transcriptome reveal candidate genes and pathways associated with hybrid sterility  in hermaphroditic Argopecten scallops. Marine Biotechnology, 2023, 25(6): 891-906. (SCI, Q1)

11. Xiaoxu Qu, Xia Wang, Bo Liu, Min Chen, Junhao Ning, Guilong Liu, Xin Xu,  Xiaotong Zhang, Kai Yu, Hui Xu, Xia Lu (通讯作者), Chunde Wang*. Potential  roles of IFI44 genes in high resistance to Vibrio in hybrids of Argopecten scallops.  Fish & shellfish immunology, 2023, 135, 108702. (SCI, 中科院二区Top)

12. Yuan Wang, Xia Lu (通讯作者)*, Chunde Wang, Junhao Ning, Min Chen, Ke  Yuan. Potential roles of FoxO in promoting longevity in larger Argopecten scallops.  Aquaculture, 2022, 561: 738690. (SCI, 中科院一区Top)

13. Hanzhi Xu, Xia Lu (通讯作者)*, Chunde Wang, Junhao Ning, Min Chen, Yuan  Wang, Ke Yuan. Potential roles of PTEN on longevity in two closely related  Argopecten scallops with distinct lifespans. Frontiers in Physiology, 2022, 13:  872562. (SCI, 中科院二区Top)

14. Ke Yuan, Xia Lu (通讯作者)*, Junhao Ning, Min Chen, Quanchao Wang, Guilong  Liu, Xin Xu, He Xu, Chunde Wang*. Potential roles of MEK1 on aging in  Argopencten scallops. Frontiers in Marine Science, 2022, 9:1057814. (SCI, 中科院二区Top)

15. Yunjun Yan, Jie Kong*, Xia Lu (通讯作者)*, Xianhong Meng, Sheng Luan, Ping  Dai, Baolong Chen, Baoxiang Cao, Kun Luo. Identification of two genes potentially  related to muscle growth from Fenneropenaeus chinensis: Activin receptor II and  Follistatin-like protein. Gene, 2021, 770:145346. (SCI, 中科院三区)

16. Yunjun Yan, Xia Lu (通讯作者)*, Jie Kong, Xianhong Meng, Sheng Luan, Ping  Dai, Baolong Chen, Baoxiang Cao, Kun Luo. Molecular characterization of  myostatin and its inhibitory function on myogenesis and muscle growth in Chinese  Shrimp, Fenneropenaeus chinensis. Gene, 2020, 758: 144986. (SCI, 中科院三区)

17. Jie Kong, Yunjun Yan, Xia Lu (通讯作者)*, Sheng Luan, Xianhong Meng, Ping  Dai, Baolong Chen, Baoxiang Cao, Guangfeng Qiang, Kun Luo. Integrative  phenotypic and gene expression data identify myostatin as a muscle growth  inhibitor in Chinese shrimp Fenneropenaeus chinensis. Scientific Reports, 2020,  10: 5985. (SCI, 中科院三区)

18. Xia Lu, Sheng Luan, Ping Dai, Kun Luo, Baolong Chen, Baoxiang Cao, Li Sun,  Yunjun Yan, Jie Kong*. Insights into the molecular basis of immunosuppression  and increasing pathogen infection severity of ammonia toxicity by transcriptome  analysis in Pacific White shrimp Litopenaeus vannamei. Fish & Shellfish  Immunology, 2019, 88: 528-539. (SCI, 中科院一区Top)

19. Xia Lu, Sheng Luan, Ping Dai, Xianhong Meng, Baoxiang Cao, Kun Luo, Jie  Kong*. iTRAQ-based comparative proteome analysis for molecular mechanism of defense against acute ammonia toxicity in Pacific White shrimp Litopenaeus  vannamei. Fish & Shellfish Immunology, 2018, 74: 52–61. (SCI, 中科院一区Top)

20. Xia Lu, Jie Kong, Xianhong Meng, Baoxiang Cao, Kun Luo, Ping Dai, Sheng  Luan*. Identification of SNP markers associated with tolerance to ammonia toxicity  by selective genotyping from de novo assembled transcriptome in Litopenaeus  vannamei. Fish & Shellfish Immunology, 2018, 73: 158–166 (SCI, 中科院一区Top)

21. 冯泽斌, 王进京, 范家伟, 刘桂龙, 徐鑫, 许贺, 王春德, 宁军号, 卢霞 (通讯作者)*. Ficolin在毛蚶抗弧菌感染中的作用. 海洋科学, 2024, 48(02): 43-57. (中文核心)

22. 于铁英，宁军号，卢霞 (通讯作者)*，王春德*. Argopecten 属扇贝种间杂交后代育性决定机制. 海洋科学，2025（综述）(中文核心)

23. 张泽斌，姜楠，唐永政，王春德*，卢霞 (通讯作者)*. Argopecten 属海湾扇贝和紫扇贝的寿命调控机制. 海洋科学，2025（综述）(中文核心)

近五年主持教学、科研项目

1. 2023/01-2026/12，IIS/FoxO 通路调控 Argopecten 属扇贝寿命的分子机制(42276147), 国家自然基金面上项目, 56 万，主持。

2. 2022/11-2026/12，厚壳贻贝黏附蛋白影响足丝附着强度性状遗传调控机制研究 (2022YFD2401700), 国家重点研发计划青年科学家项目子课题，60万，主持。

3. 2018/12-2022/12，中国对虾肌肉生长的调控机制 (2018YFD0900103),国家重点研发计划蓝色粮仓科技创新项目子课题, 79.5 万，主持。

4. 2014/01-2016/12，SOD、CAT 基因中耐氨氮相关 SNP 位点的确定及其耐氨氮机理的研究 (31302179), 国家自然科学基金青年基金项目, 23 万，主持。

5. 2022/01-2024/12，突破性扇贝新品种/系选育 (2022XCZX083)，烟台市科技计划项目，20 万，主持。

6. 2018/01-2018/12,中墨凡纳滨对虾种质差异分析及遗传评估(2018GH12)，中国水产科学研究院基本科研业务费专项国际合作项目，25 万，主持。

7. 2013/01 -2015/12，凡纳滨对虾引进群体的遗传评估及良种扩繁，中国水产科学研究院基本科研业务费专项重点学科发展储备项目，35 万，主持。

联系方式

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