姓名：卢霞
博士/副教授/硕士生导师
个人履历
学习经历：
2003-2007 西北农林科技大学 学士
2007-2012 中国科学院海洋研究所 博士（硕博连读）
工作经历：
2012-2017 中国水产科学研究院黄海水产研究所 助理研究员
2018-2020 中国水产科学研究院黄海水产研究所 副研究员
2020-2023 中国科学院烟台海岸带研究所 副研究员
2023-至今 烟台大学海洋学院 副研究员
主要科研领域与方向
主要从事贝类等水产动物重要性状遗传机制解析、生物育种、渔业资源评 价等方面的研究，利用群体遗传学、数量遗传学、分子生物学、生物信息学、分子遗传学及组学等方法和技术开展相关研究，为新品种选育提供理论依据和技术支撑。
代表性论文
1. Tieying Yu, Chunde Wang, Jiawei Fan, Rongjie Chen, Guilong Liu, Xin Xu,m Junhao Ning*, Xia Lu (通讯作者)*. Single-cell RNA sequencing revealed the roles of macromolecule epidermal growth factor receptor (EGFR) in the hybrid sterility of hermaphroditic Argopecten scallops. International Journal of Biological Macromolecules, 2024, 280:136062 (SCI, 中科院一区Top)
2. Yang Zhao, Ke Yuan, Junhao Ning, Guilong Liu, Xin Xu, Chunde Wang*, Xia Lu (通讯作者)*. Potential roles of lipases and antioxidases on longevity under nutrient restriction in two Argopecten scallops with distinct lifespans. International Journal of Biological Macromolecules, 2024, 280, 136045 (SCI, 中科院一区Top)
3. Xinyu Song, Junhao Ning, Quanchao Wang, Guilong Liu, Xin Xu, Chunde Wang*, Xia Lu (通讯作者)*. Genome-wide analysis with additive and epistasis effects reveals growth-related loci and candidate genes in hybrid Argopecten scallops. Aquaculture, 2024, 589: 741018 (SCI, 中科院一区Top)
4. Tieying Yu, Fukai Wang, Junhao Ning, Guilong Liu, Xin Xu, Chunde Wang*, Xia Lu (通讯作者)*. Effects of temperature on fertility in hybrid hermaphroditic Argopecten scallops. Aquaculture, 2024, 581: 740468. (SCI, 中科院一区Top)
5. Tieying Yu, Junhao Ning, Min Chen, Yuan Wang, Guilong Liu, Quanchao Wang, Xin Xu, Chunde Wang, Xia Lu (通讯作者)*. Hybrid sterility in hermaphroditic Argopecten scallops: Mutated mitochondrial genes and abnormal expression of nuclear genes. Aquaculture Reports, 2023, 31: 101652. (SCI, 中科院二区Top)
6. Tieying Yu, Junhao Ning, Min Chen, Fukai Wang, Guilong Liu, Quanchao Wang, Xin Xu, Chunde Wang, Xia Lu (通讯作者)*. Potential involvement of DNA methylation in hybrid sterility in hermaphroditic Argopecten scallops. Marine Biotechnology, 2023, 25(5): 701-717. (SCI, 中科院三区)
7. Yuan Wang, Chunde Wang, Junhao Ning, Tieying Yu, Ke Yuan, Guilong Liu, Quanchao Wang, Xin Xu, Bo Liu, Xia Lu (通讯作者)*. Molecular characteristics of IGF and IGF1R genes and their potential roles on longevity in two scallops with distinct lifespans. Aquaculture Reports, 2023, 33:101812. (SCI, 中科院二区Top)
8. Tieying Yu, Junhao Ning, Fukai Wang, Guilong Liu, Quanchao Wang, Xin Xu, Chunde Wang, Xia Lu (通讯作者)*. Whole-genome re-sequencing and transcriptome reveal candidate genes and pathways associated with hybrid sterility in hermaphroditic Argopecten scallops. Marine Biotechnology, 2023, 25(6): 891 906. (SCI, 中科院三区)
9. Xiaoxu Qu, Xia Wang, Bo Liu, Min Chen, Junhao Ning, Guilong Liu, Xin Xu, Xiaotong Zhang, Kai Yu, Hui Xu, Xia Lu (通讯作者), Chunde Wang*. Potential roles of IFI44 genes in high resistance to Vibrio in hybrids of Argopecten scallops. Fish & shellfish immunology, 2023, 135, 108702. (SCI, 中科院二区Top)
10. Yuan Wang, Xia Lu (通讯作者)*, Chunde Wang, Junhao Ning, Min Chen, Ke Yuan. Potential roles of FoxO in promoting longevity in larger Argopecten scallops. Aquaculture, 2022, 561: 738690. (SCI, 中科院一区Top)
11. Hanzhi Xu, Xia Lu (通讯作者)*, Chunde Wang, Junhao Ning, Min Chen, Yuan Wang, Ke Yuan. Potential roles of PTEN on longevity in two closely related Argopecten scallops with distinct lifespans. Frontiers in Physiology, 2022, 13: 872562. (SCI, 中科院二区Top)
12. Ke Yuan, Xia Lu (通讯作者)*, Junhao Ning, Min Chen, Quanchao Wang, Guilong Liu, Xin Xu, He Xu, Chunde Wang*. Potential roles of MEK1 on aging in Argopencten scallops. Frontiers in Marine Science, 2022, 9:1057814. (SCI, 中科 院二区Top)
13. Yunjun Yan, Jie Kong*, Xia Lu (通讯作者)*, Xianhong Meng, Sheng Luan, Ping Dai, Baolong Chen, Baoxiang Cao, Kun Luo. Identification of two genes potentially related to muscle growth from Fenneropenaeus chinensis: Activin receptor II and Follistatin-like protein. Gene, 2021, 770:145346. (SCI, 中科院三区)
14. Yunjun Yan, Xia Lu (通讯作者)*, Jie Kong, Xianhong Meng, Sheng Luan, Ping Dai, Baolong Chen, Baoxiang Cao, Kun Luo. Molecular characterization of myostatin and its inhibitory function on myogenesis and muscle growth in Chinese Shrimp, Fenneropenaeus chinensis. Gene, 2020, 758: 144986. (SCI, 中科院三区)
15. Jie Kong*, Yunjun Yan, Xia Lu (通讯作者)*, Sheng Luan, Xianhong Meng, Ping Dai, Baolong Chen, Baoxiang Cao, Guangfeng Qiang, Kun Luo. Integrative phenotypic and gene expression data identify myostatin as a muscle growth inhibitor in Chinese shrimp Fenneropenaeus chinensis. Scientific Reports, 2020, 10: 5985. (SCI, 中科院三区)
16. Xia Lu, Sheng Luan, Ping Dai, Kun Luo, Baolong Chen, Baoxiang Cao, Li Sun, Yunjun Yan, Jie Kong*. Insights into the molecular basis of immunosuppression and increasing pathogen infection severity of ammonia toxicity by transcriptome analysis in Pacific White shrimp Litopenaeus vannamei. Fish & Shellfish Immunology, 2019, 88: 528-539. (SCI, 中科院一区Top)
17. Xia Lu, Sheng Luan, Ping Dai, Xianhong Meng, Baoxiang Cao, Kun Luo, Jie Kong*. iTRAQ-based comparative proteome analysis for molecular mechanism of defense against acute ammonia toxicity in Pacific White shrimp Litopenaeus vannamei. Fish & Shellfish Immunology, 2018, 74: 52–61. (SCI, 中科院一区Top)
18. Xia Lu, Jie Kong, Xianhong Meng, Baoxiang Cao, Kun Luo, Ping Dai, Sheng Luan*. Identification of SNP markers associated with tolerance to ammonia toxicity by selective genotyping from de novo assembled transcriptome in Litopenaeus vannamei. Fish & Shellfish Immunology, 2018, 73: 158–166 (SCI, 中科院一区 Top)
19. Xia Lu, Sheng Luan, Baoxiang Cao, Xianhong Meng, Juan Sui, Ping Dai, Kun Luo, Dengchun Hao, Xiaoli Shi, Guomin Han, Jie Kong*. Estimation of genetic parameters and genotype-by-environment interactions related to acute ammonia stress in Pacific white shrimp (Litopenaeus vannamei) juveniles at two different salinity levels. PLos One, 2017, 12(3): e0173835. (SCI, 中科院三区)
20. Xia Lu, Sheng Luan, LongYang Hu, Yong Mao, Ye Tao, ShengPing Zhong, Jie Kong*. High resolution genetic linkage mapping, high temperature tolerance and growth-related quantitative trait locus (QTL) identification in Marsupenaeus japonicus. Molecular Genetics and Genomics, 2016, 291:1391-1405. (SCI, 中科院三区)
21. 冯泽斌, 王进京, 范家伟, 刘桂龙, 徐鑫, 许贺, 王春德, 宁军号, 卢霞 (通讯作者)*. Ficolin 在毛蚶抗弧菌感染中的作用. 海洋科学, 2024, 48(02): 43-57.
近五年主持教学、科研项目
1. 2023/01-2026/12，IIS/FoxO 通路调控 Argopecten 属扇贝寿命的分子机制 (42276147), 国家自然基金面上项目, 主持。
2. 2022/11-2026/12，厚壳贻贝黏附蛋白影响足丝附着强度性状遗传调控机制研究 (2022YFD2401700), 国家重点研发计划青年科学家项目子课题，主持。
3. 2018/12-2022/12，中国对虾肌肉生长的调控机制 (2018YFD0900103), 国家重点研发计划蓝色粮仓科技创新项目子课题, 主持。
4. 2014/01-2016/12，SOD、CAT基因中耐氨氮相关SNP位点的确定及其耐氨氮机理的研究 (31302179), 国家自然科学基金青年基金项目, 主持。
5. 2022/01-2024/12，突破性扇贝新品种/系选育 (2022XCZX083)，烟台市科技计划项目，主持。
6. 2018/01-2018/12,中墨凡纳滨对虾种质差异分析及遗传评估(2018GH12)，中国水产科学研究院基本科研业务费专项国际合作项目，主持。
7. 2013/01 -2015/12，凡纳滨对虾引进群体的遗传评估及良种扩繁，中国水产科学研究院基本科研业务费专项重点学科发展储备项目，主持。
联系方式
邮箱：luxia_0202@163.com
